H.R.6281: To provide States with the resources needed to rid our schools of performance-enhancing drug use.

High School Sports Anti-Drug Act - Directs the Secretary of Education, acting through the Assistant Deputy Secretary of the Office of Safe and Drug-Free Schools, to award competitive grants to states to develop and carry out statewide pilot programs that randomly test secondary school students for performance-enhancing drug use.

Requires a parent's or guardian's written consent before a student may be tested.

Directs grantees to: (1) provide recovery, counseling, and treatment programs for students who test positive for performance-enhancing drug use; and (2) spend at least 10% of grant funds on preventing such drug use.